Endocrine Abstracts

Introduction: Insulinoma, despite its low incidence of 0.4%, it is the most common functioning pancreatic neuroendocrine tumor. Most are benign, solitary and sporadic. Around 10% can be malignant and 5-10% are part of MEN-1. On certain occasions, the differential diagnosis is difficult when there is a history of Diabetes Mellitus (DM). Our objective was to describe clinical-epidemiological data and its diagnostic-therapeutic management.Materials and Meth...

Introduction: Hyperthyroidism has been described as a rare cause of pulmonary hypertension (PH) as well as systemic arteriovenous fistulas. However, we describe a case of pulmonary hypertension secondary to an intrathyroid arteriovenous fistula, not previously described in the literature.Case report: A 56 year old woman followed in our consultations with multinodular goiter and a long standing hyperthyroidism, secondary to Graves Basedow disease with dif...

Introduction: Although the most common causes of hyperprolactinemia are prolactinoma and iatrogenic, another possible cause is severe primary hypothyroidism, in which the increase of prolactin is a cause of pituitary stimulation by TRH, and can be presented with pituitary hyperplasia.Case report: A 31-year-old woman who comes to endocrinology clinic for hyperprolactinemia, which was detected by symptoms of amenorrhea–galactorrhea. After normal pregn...

Introduction: Allergy is an uncommon side-effect of insulin treatment in which desensitization represents an alternative when initial approaches are not effective. Autoimmune pancreatitis (AIP) is an even more rare disease that generally has a successful response to corticosteroids. The case of a 50-year-old diabetic man who developed both processes sequentially is presented.Case report: The patient was admitted for acute diabetes mellitus (DM) decompens...

Methods: Restrospective descriptive study of patients who underwent ETPS for pituitary adenoma removal performed by the same surgical team in Virgen del Rocio Hospital of Seville from January 2014 to January 2019.Results: 174 patients had a pituitary adenoma (44 GH, 36 ACTH, 94 Non functioning). 54.02% were female. In acromegaly, 39 (88.63%) patients were operated by ETPS as initial approach. 20 (51.28%) patients had cavernous sinus invation. At outcome ...

Introduction: major complications of thyroid surgery include; injury to the recurrent laryngeal nerve that can cause dysphonia and acute respiratory distress, postsurgical hematoma, infection and hypoparathyroidism, which can be transient or permanent.Objective: to analyze the complications observed after performing thyroid surgery with different pre-surgical diagnoses in our center.Methods: retrospective descriptive study of thyro...

Introduction: The Bethesda system gives each Fine Needle Aspiration (FNA) category a risk of malignancy (B1: 5-10%, B2: 0-3%, B3: 10-30%, B4: 25-40%, B5: 50-75%, B6: 97-99%). Based on this risk, therapeutic decisions are made that influence the patient’s life. It is important to check whether the percentage of malignancy obtained in our daily clinical practice is similar to that expected according to this system.Aim: To check whether the percentage ...

Background: Patients with Cushing’s syndrome (CS) in remission show residual cardiometabolic derangements leading to increased cardiovascular risk. Impaired characteristics of gut microbiome (dysbiosis), such as richness, diversity and composition, have been associated with several cardiometabolic risk factors, including obesity, insulin resistance and atherosclerosis. Whether CS patients present with intestinal dysbiosis is currently unknown. Our study was aimed at evalu...

Introduction: Adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome (CS) secondary to an ectopic source is an uncommon condition, accounting for 4-5% of all cases of CS and between 9-18% of cases of ACTH-dependent CS. Although numerous malignancies have been associated with ectopic ACTH syndrome (EAS), lung neuroendocrine tumours (NETs) are the most common. Refractory hypokalemia can be the presenting feature in EAS and is seen in up to 80% of cases. We present ...

Introduction: Central pontine myelinolysis (CPM) is a rare and potentially life-threatening complication of a sudden rise in serum osmolality. Along with extrapontine myelinolysis, it is part of the osmotic demyelination syndrome (ODS). Known risk factors include severe hyponatremia, alcoholism, thiazide use, hypokalemia, and malnourishment.Case report: We report the case of a 31-year-old-male with history of alcohol and cannabis dependence, who had atte...